Erfassung hämodynamischer Parameter bei Patienten mit chronischer thromboembolischer pulmonaler Hypertonie mittels MRT vor und nach Thrombendarteriektomie

Autor: CP Heussel, E. Mayer, Manfred Thelen, K.-F. Kreitner, HU Kauczor, Sebastian Ley, T. Kramm
Rok vydání: 2003
Předmět:
Zdroj: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 175:1647-1654
ISSN: 1438-9010
1438-9029
DOI: 10.1055/s-2003-45340
Popis: Purpose: To evaluate the potential of MRI to grade cardiac impairment and pulmonary hypertension in patients with chronic thromboembolic pulmonary hypertension (CTEPH) in comparison with invasive pressure measurements before and after surgery. Materials and Methods: We examined 35 patients with CTEPH before and after pulmonary thromboendarterectomy (PTE). For assessment of hemodynamics, velocity-encoded segmented GE-sequences (pulmonary arteries and ascending aorta) and segmented cine GE-sequences along the short axis of the heart were performed. The analysis comprised calculation of ejection fractions, peak velocities, mean pulmonary arterial flow and vessel diameter. 10 volunteers served as controls. Flow measurements were compared to invasively measured mean pulmonary arterial pressure (MPAP) and vascular resistance (PVR). Results: Compared to volunteers, CTEPH-patients showed significantly reduced right ventricular ejection fractions (p < 0.001), pulmonary peak velocity (p < 0.001) and significantly increased diameters of the pulmonary arteries (p
Databáze: OpenAIRE