The chemical and biological properties of methoxyfenozide, a new insecticidal ecdysteroid agonist
| Autor: | Richard K Jansson, Glenn Richard Carlson, Tarlochan S. Dhadialla, Ricky Hunter, Zev Lidert, Richard A. Slawecki, Christine S. Jany |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Agonist
Tortricidae Ecdysteroid medicine.medical_specialty biology medicine.drug_class fungi 20-Hydroxyecdysone General Medicine Pharmacology biology.organism_classification chemistry.chemical_compound Endocrinology chemistry Insect Science Internal medicine Insect growth regulator medicine Noctuidae Ecdysone receptor Agronomy and Crop Science Pyralidae |
| Zdroj: | Pest Management Science. 57:115-119 |
| ISSN: | 1526-4998 1526-498X |
| DOI: | 10.1002/1526-4998(200102)57:2<115::aid-ps245>3.0.co;2-a |
| Popis: | Methoxyfenozide [N-tert-butyl-N'-(3-methoxy-o-toluoyl)-3,5-xylohydrazide; RH-2485] is the newest diacylhydrazine insecticide to reach the marketplace. It binds with very high affinity to the ecdysone receptor complex (EcR:USP) in lepidopteran insects [Kd = 0.5 nM (Plodia)], where it functions as a potent agonist, or mimic, of the insect molting hormone, 20-hydroxyecdysone (20E). Methoxyfenozide exhibits high insecticidal efficacy against a wide range of important caterpillar pests, including many members of the family Pyralidae, Pieridae, Tortricidae and Noctuidae. It is most effective when ingested by the target caterpillar, but it also has some topical and ovicidal properties. It is modestly root systemic, but not significantly leaf-systemic. Evidence collected to date indicates that methoxyfenozide has an excellent margin of safety to non-target organisms, including a wide range of non-target and beneficial insects. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text