| Autor: |
G. Nardin, Lucilla Dolzani, G. Mestroni, S. Zorzet, Franco Quadrifoglio, Wahib M. Attia, G. Sava, Enzo Alessio, Sabina Cauci, M. Tamaro, M. Calligaris, C. Monti-Bragadin |
| Rok vydání: |
1988 |
| Předmět: |
|
| Zdroj: |
Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy ISBN: 9781461289678 |
| Popis: |
After the discovery of the antineoplastic activity of cis-PtCl2(NH3)2 (cisplatin, cis-DDP) (1), several Pt(II) derivatives have been synthesized and tested with the aim of developing new drugs having more pronounced antitumor activity and reduced host toxicity (2). Despite this effort, up to now only 3 out of more than 1000 platinum derivatives tested have reached the stage of clinical trials (3). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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