Wide QRS-T Angle on the 12-Lead ECG as a Predictor of Sudden Death Beyond the LV Ejection Fraction

Autor:	Carmen Teodorescu, Sumeet S. Chugh, Aapo L. Aro, M.P.H. Jonathan Jui M.D., Kelvin C.M. Chua, Kyndaron Reinier, Sandeep G. Nair, Audrey Uy-Evanado, B S Harpriya Chugh
Rok vydání:	2016
Předmět:	medicine.medical_specialty Ejection fraction medicine.diagnostic_test business.industry Sudden cardiac arrest Stroke volume 030204 cardiovascular system & hematology Left ventricular hypertrophy medicine.disease Sudden death 03 medical and health sciences 0302 clinical medicine Physiology (medical) Predictive value of tests Internal medicine Heart rate cardiovascular system Cardiology medicine cardiovascular diseases 030212 general & internal medicine medicine.symptom Cardiology and Cardiovascular Medicine business Electrocardiography
Zdroj:	Journal of Cardiovascular Electrophysiology. 27:833-839
ISSN:	1045-3873
Popis:	QRST-angle and Sudden Cardiac DeathIntroduction Improvements in risk stratification for sudden cardiac arrest (SCA) will require discovery of markers that extend beyond the LV ejection fraction (LVEF). The frontal QRS-T angle has been shown to predict risk of SCA but the value of this marker independent of the LVEF has not been investigated. Methods and Results Cases of adult SCA with an archived electrocardiogram (12-lead ECG) available before the event, with a computable frontal QRS-T angle, were identified from the Oregon Sudden Unexpected Death Study (Oregon SUDS) ongoing in the Portland, Oregon metro area. A total of 666 SCA cases (mean age 67.2 years; 95% CI, 52.3–82.1 years; 68.6% males) were compared to 863 controls (mean age 66.6 years, 55.2–78.0 years; 68.1% males; 75.0% had CAD) from the same geographical region. The mean frontal QRS-T angle was wider in cases (74o; 95% CI, 17o–131o) compared to controls (51o; 95% CI, 5o–97o; P< 0.0001). A frontal QRS-T angle of more than 90o remained associated with increased risk of SCD after adjusting for age, gender, heart rate, prolonged intraventricular conduction, electrocardiographic left ventricular hypertrophy (ECG LVH), baseline comorbidities, and left ventricular ejection fraction (LVEF) (OR 2.2; 95% CI, 1.60–3.09; P< 0.0001). Conclusion A wide QRS-T angle greater than 90o is associated with an increased risk of SCA independent of the left ventricular ejection fraction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::baee97789c0fc423255e2b42a6811b95 https://doi.org/10.1111/jce.12989 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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