A Short and High Yield Access to Glycosyl Donors of Amino-Deoxy-Sugars of Biological Relevance

Autor:	Carole Mouton, François Tillequin, Claude Monneret, J.‐C. Florent, E. Seguin, Laurent Daley
Rok vydání:	1998
Předmět:	Serine chemistry.chemical_compound Epipodophyllotoxin Glucoside Chemistry Stereochemistry Yield (chemistry) Organic Chemistry Glycosyl
Zdroj:	Synthetic Communications. 28:61-73
ISSN:	1532-2432 0039-7911
Popis:	Synthesis of silylglycosides of 3-azido-2-deoxy-L-arabino- and ribo-hexopyranoses 4 and 5 has been achieved in 3 steps and 44,6% and 18% overall yields, respectively. The corresponding N-trifluoroacetamido derivatives 9 and 10 were further prepared in 3 steps. Usefulness of 4,9, and 10 was demonstrated by coupling with epipodophyllotoxin derivatives or with suitably protected amino-acids such as serine or 4-OH-phenylglycine or 4-OH-phenylglycinyl glucoside.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b89c74c5dc4e54fb60c4903cb9149940 https://doi.org/10.1080/00397919808005074 Zobrazit plný text záznamu