AB0325 Comparison of Activity Score DAS28-ESR and DAS28 -CRP in Patients with Rheumatoid Arthritis
| Autor: | L. Medrare, I. Ben Slama, H. Rkain, S. El Kabbaj, Najia Hajjaj-Hassouni, Fadoua Allali, A. Ngeuleu, T. Lakhdar |
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| Rok vydání: | 2014 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty medicine.diagnostic_test medicine.drug_class business.industry Immunology Morning stiffness Disease medicine.disease Logistic regression General Biochemistry Genetics and Molecular Biology Das28 esr Rheumatology immune system diseases Erythrocyte sedimentation rate Rheumatoid arthritis Internal medicine medicine Physical therapy Immunology and Allergy Corticosteroid In patient skin and connective tissue diseases business |
| Zdroj: | Annals of the Rheumatic Diseases. 73:912.2-912 |
| ISSN: | 1468-2060 0003-4967 |
| DOI: | 10.1136/annrheumdis-2014-eular.5807 |
| Popis: | Objectives To compare the disease activity score (DAS)28- ESR versus DAS28 -CRP, and to determine the factors that might influence their difference. Methods Patients with RA were included in a cross-sectional study. We have collected the demographic characteristics and the characteristics of the RA: duration of evolution, morning stiffness in minutes, functional impact of the disease assessed by the HAQ (Health Assessment Questionnaire), and current corticosteroid dose. The disease activity was assessed by the DAS28-ESR and DAS28-CRP. A simple correlation between DAS28-ESR and DAS28-CRP was performed. We considered a difference between DAS28-ESR and DAS28-CRP as significant when it is greater than or equal to 0.6 [1]. Factors influencing this difference were tested by univariate then multivariate logistic regression. Results 103 patients were included with a female predominance (87.4%). Mean age was 49.7±11.4 years. Median disease duration was 8 years [3-14]. There was a strong positive correlation between the two indexes of 0.91 (p Conclusions Our study shows a strong positive correlation between the DAS28-ESR and DAS28 -CRP. But DAS VS 28 would be higher than the DAS28 CRP in patients with high pain intensity and significant functional impairment. References Are the C-reactive protein values and erythrocyte sedimentation rate equivalent when estimating the 28-joint disease activity score in rheumatoid arthritis? Clin Exp Rheumatol. 2008 Sep-Oct;26(5):769-75. Disclosure of Interest None declared DOI 10.1136/annrheumdis-2014-eular.5807 |
| Databáze: | OpenAIRE |
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