Ictal SPECT findings in typical absence seizures
| Autor: | B. David Collier, Jeanne Pallagi, Robert S. Hellman, George L. Morris, Selim R. Benbadis |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Typical absence seizure business.industry General Neuroscience Single-photon emission computed tomography Electroencephalography medicine.disease Ictal-Interictal SPECT Analysis by SPM Childhood absence epilepsy Anesthesia Internal medicine Hyperventilation medicine Cardiology Ictal Neurology (clinical) Generalized epilepsy medicine.symptom business |
| Zdroj: | Journal of Epilepsy. 11:187-190 |
| ISSN: | 0896-6974 |
| DOI: | 10.1016/s0896-6974(98)00016-4 |
| Popis: | Single photon emission computed tomography (SPECT) is known to reveal localized hyperperfusion during partial seizures, but is rarely performed in idiopathic generalized epilepsies. We report the ictal SPECT findings in a typical absence seizure. This 35-year-old woman with childhood absence epilepsy underwent prolonged electroencephalogram (EEG)-video monitoring, during which many stereotyped typical absence seizures were recorded. These consisted of brief staring spells with arrest of activity, associated with generalized 3 Hz spike-wave complexes on EEG. Following intravenous (i.v.) injection of 17.6 millicuries of Tc-99m Bicisate, SPECT was performed. The injection was performed during hyperventilation that induced a typical absence. Compared to the baseline SPECT scan that was normal, the ictal scan showed a generalized reduction in cortical activity. These findings do not support the "cortical" theory of typical absence seizures and the genesis of the 3 Hz spike-wave complexes. They may indeed support the subcortical or "centrencephalic" hypothesis. |
| Databáze: | OpenAIRE |
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