Offline Error Detection in MEDA-Based Digital Microfluidic Biochips Using Oscillation-Based Testing Methodology
| Autor: | Krishnendu Chakrabarty, Noohul Basheer Zain Ali, Vineeta Shukla, Nor Hisham Hamid, Fawnizu Azmadi Hussin |
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| Rok vydání: | 2017 |
| Předmět: |
Engineering
business.industry Multiphysics 020208 electrical & electronic engineering Microfluidics Hardware_PERFORMANCEANDRELIABILITY 02 engineering and technology 020202 computer hardware & architecture chemistry.chemical_compound Reliability (semiconductor) chemistry Scalability Hardware_INTEGRATEDCIRCUITS 0202 electrical engineering electronic engineering information engineering Electronic engineering Digital microfluidics Hardware_ARITHMETICANDLOGICSTRUCTURES Electrical and Electronic Engineering Fault model Biochip business MEDA |
| Zdroj: | Journal of Electronic Testing. 33:621-635 |
| ISSN: | 1573-0727 0923-8174 |
| DOI: | 10.1007/s10836-017-5678-5 |
| Popis: | Digital microfluidics is an emerging class of lab-on-a-chip system. Reliability is a critical performance parameter as these biochips are employed in various safety-critical biomedical applications. With the introduction of highly scalable, reconfigurable and field programmable Micro-Electrode-Dot-Array (MEDA) architecture, the limitation of conventional DMFBs in varying the droplet size/volume in fine grain manner has been resolved. However, the MEDA-based biochips must be adequately tested upon fabrication to guarantee the correctness of bioassays. In this work, an offline testing approach based on Oscillation-Based Testing (OBT) methodology is presented for MEDA-based digital microfluidic biochips. Various simulations were performed for droplet-electrode short fault model involving single and multiple micro-electrodes. Furthermore, the loss of droplet volume due to the presence of defect was analyzed using COMSOL Multiphysics. The simulation results based on PSpice and COMSOL show that the proposed approach is effective for detecting defects in MEDA-based biochips. |
| Databáze: | OpenAIRE |
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