S50 A randomised clinical trial of azithromycin versus standard care in ambulatory COVID-19 – the ATOMIC2 trial

Autor: J Melhorn, Samer Elkhodair, Ruth Knight, Phil Moss, Jonathan Underwood, A Wang, Vicki S Barber, M Jabeen, Susan J Dutton, Tanya Baron, Lucy Cureton, Daniel Lasserson, Sophie B. Morgan, Jennifer L Cane, David Clarke, Duncan Richards, Rajendar Garlapati, Hinks Tsc., Ian D. Pavord, Joanna Black, Fleur Cantle, Graham Johnson
Rok vydání: 2021
Předmět:
Zdroj: Developing treatments for COVID-19.
Popis: Background The antibacterial, anti-inflammatory and antiviral properties of azithromycin suggest therapeutic potential against COVID-19. Randomised data in mild-moderate disease are lacking. We assessed whether azithromycin is effective in reducing hospitalisation in patients with mild-moderate COVID-19. Methods This open-label, randomised superiority clinical trial at 19 centres in the United Kingdom enrolled adults, ≥18 years, presenting to hospitals with clinically-diagnosed highly-probable or confirmed COVID-19 infection, with
Databáze: OpenAIRE