| Autor: |
Francesco Chiarelli, Neri Pucci, Alessandra Scaparrotta, Daniele Rapino, N.P. Consilvio, Marzia Cerasa, S. Di Pillo, Anna Cingolani, M. Di Gioacchino, Marina Attanasi |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
International Journal of Immunopathology and Pharmacology. 26:795-800 |
| ISSN: |
0394-6320 |
| DOI: |
10.1177/039463201302600327 |
| Popis: |
We describe the case of a child affected by milk-protein induced enterocolitis, in which oral challenge with corn was performed without symptoms after a negative specific Atopy Patch Test. Food protein-induced enterocolitis syndrome (FPIES) is an uncommon nonIgE-mediated gastrointestinal food hypersensitivity of infancy, characterized by severe vomiting and diarrhea arising within 1 to 3 hours after ingestion of the causative food. Little is known about the pathophysiology of FPIES. The absence of food-specific IgE as demonstrated by negative skin prick tests suggests that the disease is not caused by an early onset IgE-mediated reaction. Atopy Patch Test has been described as sensitive and predictive in this syndrome. The hypothesis on the immunological pathogenesis has been discussed on the basis of literature data. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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