Surgical Planning after Neoadjuvant Treatment in Breast Cancer: A Multimodality Imaging-Based Approach Focused on MRI

Autor: Marco Conti, Francesca Morciano, Enida Bufi, Anna D’Angelo, Camilla Panico, Valerio Di Paola, Elisabetta Gori, Gianluca Russo, Giovanni Cimino, Simone Palma, Paolo Belli, Riccardo Manfredi
Rok vydání: 2023
Předmět:
Zdroj: Cancers. 15:1439
ISSN: 2072-6694
DOI: 10.3390/cancers15051439
Popis: Neoadjuvant chemotherapy (NACT) today represents a cornerstone in the treatment of locally advanced breast cancer and highly chemo-sensitive tumors at early stages, increasing the possibilities of performing more conservative treatments and improving long term outcomes. Imaging has a fundamental role in the staging and prediction of the response to NACT, thus aiding surgical planning and avoiding overtreatment. In this review, we first examine and compare the role of conventional and advanced imaging techniques in preoperative T Staging after NACT and in the evaluation of lymph node involvement. In the second part, we analyze the different surgical approaches, discussing the role of axillary surgery, as well as the possibility of non-operative management after-NACT, which has been the subject of recent trials. Finally, we focus on emerging techniques that will change the diagnostic assessment of breast cancer in the near future.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje