Integrated mathematical models for describing complex biological processes

Autor:	A. M. Mishchenko, Olga V. Petrovskaya, Nikita V. Ivanisenko, Elena L. Mishchenko, Evgeny D. Petrovskiy, Vladimir A. Ivanisenko
Rok vydání:	2017
Předmět:	0301 basic medicine 03 medical and health sciences 030104 developmental biology Mathematical model Computer science Biophysics Identification (biology) Ct imaging Neuroscience Brain function
Zdroj:	Biophysics. 62:778-795
ISSN:	1555-6654 0006-3509
DOI:	10.1134/s0006350917050141
Popis:	This review describes integrated mathematical models of processes, such as calcium homeostasis, pathogen–host interaction (with hepatitis C virus as a pathogen), and the response of the human brain to a stimulating event. It is shown that integrated mathematical models provide a deeper insight into the mechanisms and conditions that lead to the development of diseases of different natures (musculoskeletal disorders, viral infections, and various impairments in brain function) and aid identification of the key targets and conditions for a directed effect of new generation drugs, as well as the interpretation of the results of state-of-theart CT imaging.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b6a68a5c7028b9824d7acd469d7f7087 https://doi.org/10.1134/s0006350917050141 Zobrazit plný text záznamu Full text from SpringerLink