Mixed Ternary Complexes of Sparfloxacin with Some Biologically Important Amino Acids
| Autor: | A. A. El-Sayed, Rasha M. Kamel, Reham Ali, W. H. Hegazy |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Alanine
chemistry.chemical_classification biology Chemistry Potentiometric titration Biophysics Phenylalanine 02 engineering and technology 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Amino acid 020401 chemical engineering Stability constants of complexes Valine Aspartic acid biology.protein 0204 chemical engineering Physical and Theoretical Chemistry Bovine serum albumin Molecular Biology Nuclear chemistry |
| Zdroj: | Journal of Solution Chemistry. 50:340-354 |
| ISSN: | 1572-8927 0095-9782 |
| DOI: | 10.1007/s10953-021-01057-8 |
| Popis: | Potentiometric measurements for the interaction of sparfloxacin (SPFX) and the metal ions Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) with the amino acids (AA) aspartic acid, alanine, valine, glutamic acid, threonine, methionine, arginine, phenylalanine were studied. The formation constants for the 1:1 binary and 1:1:1 ternary complexes in 10% (v/v) ethanol–water, I = 0.1 mol⋅L−1 KNO3 and 25 °C were measured. The values were refined using the HYPERQUAD computer program. The binding constants of M(II)–SPFX binary complexes with bovine serum albumin using absorption titration experiments were also determined. |
| Databáze: | OpenAIRE |
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