Endocrinological and immunological variables sensitive to psychosocial factors of possible relevance to work-related musculoskeletal disorders
| Autor: | Töres Theorell, Hans-Martin Hasselhorn, null Music Norrtälje Study Group |
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| Rok vydání: | 2002 |
| Předmět: | |
| Zdroj: | Work & Stress. 16:154-165 |
| ISSN: | 1464-5335 0267-8373 |
| DOI: | 10.1080/02678370210150837 |
| Popis: | Research has indicated that energy mobilization in the body is associated with lowered anabolism, which promotes the repair and restoration of damaged or worn out tissues. Problems may arise when adversity requires energy mobilization for a long period of time. Increased tissue vulnerability can be anticipated. There is evidence that growth hormone has anabolic activity, as do the male and female hormones testosterone and oestradiol and a precursor of both these anabolic steroids, dehydroepiandrosterone sulphate (DHEA-s). The levels of these in serum/plasma may be lowered during periods of adversity. It can therefore be hypothesized that due to the lowering of anabolic activity, tissues are at risk during periods of stress (part of the 'anabolic hypothesis') and that this will be reflected in musculoskeletal symptoms. Furthermore, low anabolic activity predicts more long-lasting illness/disability. In the present study, blood samples were drawn from representative groups of men and women with musculoskele... |
| Databáze: | OpenAIRE |
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