The Cumulative Risk to Human Health of Pharmaceuticals in New Jersey Surface Water

Autor:	Nicholas M. Roden, Edward V. Sargent, Jun-Yan Hong, George T. DiFerdinando, Mark G. Robson
Rok vydání:	2014
Předmět:	Cumulative risk Human health Health Toxicology and Mutagenesis Ecological Modeling Environmental health Water source Health impact Environmental science Cumulative hazard Risk assessment Pollution Surface water Cumulative effect
Zdroj:	Human and Ecological Risk Assessment: An International Journal. 21:280-295
ISSN:	1549-7860 1080-7039
Popis:	Surface water in New Jersey is used by many residential drinking water facilities. Like many water sources it is contaminated by upstream industrial and residential sources, including pharmaceutical residues. This research examines the concentrations of 18 pharmaceuticals in 30 New Jersey locations, their acceptable daily exposures (ADE), and potential drug–drug interactions (DDI). The surface water data was provided by the U.S. Geological Survey (USGS). ADEs for human health were set for each pharmaceutical in the study. The pharmaceuticals were evaluated for known adverse health interactions and their potential health impact. These factors were brought together using a cumulative hazard index (HI) risk assessment calculation to assess the overall risk of pharmaceuticals in NJ surface water to human health. When examining the potential for DDI in this assessment, the risk increased but not appreciably. The HI for the sample locations ranged from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b4b927b168feee386ea93e391e9bc4a1 https://doi.org/10.1080/10807039.2014.913439 Zobrazit plný text záznamu