NbCl5 and AgClO4 Promoted Regio-Selective Acylation of Indoles

Autor: Vinod T. Kamble, Hari R. Pawar, Narendra R. Kamble
Rok vydání: 2020
Předmět:
Zdroj: Asian Journal of Chemistry. 32:317-321
ISSN: 0975-427X
0970-7077
DOI: 10.14233/ajchem.2020.22419
Popis: In present study, an efficient and simple strategy towards chemo-selective and regio-selective acylation of indole using NbCl5 and AgClO4 catalyst are reported. This method utilizes the catalytic potentiality of NbCl5 and AgClO4 towards acylation of unprotected indoles in a synergistic manner. The combination of these catalytic system results into numerous advantages such as excellent yields of product, short reaction times and easier isolation of products.
Databáze: OpenAIRE