Tension in tumour cells keeps metabolism high

Autor:	Valerie M. Weaver, Nadia M. E. Ayad
Rok vydání:	2020
Předmět:	0301 basic medicine Multidisciplinary Cellular metabolism Chemistry Tension (physics) Normal tissue Metabolism Cell biology Protein filament 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Microtubule 030220 oncology & carcinogenesis Glycolysis Cytoskeleton
Zdroj:	Nature. 578:517-518
ISSN:	1476-4687 0028-0836
DOI:	10.1038/d41586-020-00314-y
Popis:	Tumours are often stiffer than normal tissues and show abnormally fast metabolism of glucose. It emerges that the link between these two traits involves tension in a network of protein filaments in cells. Cytoskeletal tension modulates cellular metabolism.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b32936cc3de2c0ad6e47709c1a6a4fec https://doi.org/10.1038/d41586-020-00314-y Zobrazit plný text záznamu Full text from SpringerLink