Two new compounds isolated from the entomogenous fungus Fusarium sp. LGWB-7
| Autor: | Chun Qing Li, Sha Sha Liu, Du Qiang Luo, Fan Dong Kong, You Xing Zhao, Qing Yun Ma, Qing Yi Xie, Li Man Zhou |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Fusarium
biology 010405 organic chemistry Chemistry Plant Science Fungus biology.organism_classification 01 natural sciences Biochemistry Harmonia axyridis 0104 chemical sciences Microbiology HeLa Human tumor 010404 medicinal & biomolecular chemistry Cell culture Ic50 values Cytotoxicity Agronomy and Crop Science Biotechnology |
| Zdroj: | Phytochemistry Letters. 41:74-77 |
| ISSN: | 1874-3900 |
| Popis: | Two new compounds, named fusariumtrin A (1) and climacomontaninate D (2), together with eight known ones were isolated from the rice culture of the Fusarium sp. LGWB-7, an entomogenous fungus isolated from the Harmonia axyridis. The structures of the new compounds were elucidated by the analysis of 1D and 2D spectroscopic data as well as mass spectrum (MS). Compound 10 showed cytotoxicity against K562, A549, SGC-7901, and Hela human tumor cell lines with IC50 values of 1.46, 13.97, 9.34, and 6.64 μM, respectively. |
| Databáze: | OpenAIRE |
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