Effect of Estrogenic Hormone on Hyperthyroidism

Autor: Aaron A. Farbman
Rok vydání: 1944
Předmět:
Zdroj: The Journal of Clinical Endocrinology & Metabolism. 4:17-22
ISSN: 1945-7197
0021-972X
DOI: 10.1210/jcem-4-1-17
Popis: THAT a relationship exists between the ovary and the thyroid has long been recognized. At the onset of puberty, during pregnancy and lactation and at the menopause the thyroid often increases in size. In hyperthyroidism, irregular menstruation, menorrhagia and particularly amenorrhea are frequently observed. These menstrual disturbances, particularly menorrhagia, also occur in hypothyroidism. These disorders appear to be due to the non-specific or perhaps the specific action of the thyroid hormone on gonadal cells. Uotila (1) found that thyroxin produces atrophy of the seminal vesicles of the rat, probably by depressing the output of gonadotropic hormones of the anterior lobe of the pituitary. On the other hand Howell, Drips and Fisher (2) have observed excessive amounts of gonadotropic principles in the urine of both hyperthyroid and hypothyroid subjects. In any event there is considerable evidence that the gonads are affected by the thyroid. That conversely, the thyroid is affected by the gonads has rec...
Databáze: OpenAIRE