ANCA-Associated Vasculitides—An Update
| Autor: | Johanna Kegel, Torsten Kirsch |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry ANCA-Associated Vasculitides Cytoplasmic antibody Necrotizing glomerulonephritis medicine.disease Pathophysiology respiratory tract diseases Granulomatous inflammation medicine.anatomical_structure immune system diseases Clinical diagnosis Immunology medicine cardiovascular diseases skin and connective tissue diseases business Vasculitis Respiratory tract |
| Zdroj: | Health. :1767-1779 |
| ISSN: | 1949-5005 1949-4998 |
| Popis: | Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are characterized by destruction of small vessels, granulomatous inflammation of the respiratory tract and necrotizing glomerulonephritis. This review describes the clinical diagnosis and therapy as well as the patho-physiology of ANCA-associated vasculitides with a specific focus on the interplay of ANCAs with activated neutrophils and the deleterious pathophysiological consequences of neutrophil-endothelium interaction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|