A self-optimized software tool for quantifying the degree of left ventricle hyper-trabeculation
| Autor: | Javier Cuenca, Gregorio Bernabé, José D. Casanova, Josefa González-Carrillo |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
020203 distributed computing
education.field_of_study Ventricular cavity Computer science Software tool Population Cardiomyopathy Hypertrophic cardiomyopathy 02 engineering and technology medicine.disease Theoretical Computer Science medicine.anatomical_structure Hardware and Architecture Ventricle 0202 electrical engineering electronic engineering information engineering medicine education Cardiac magnetic resonance Software Information Systems Biomedical engineering |
| Zdroj: | The Journal of Supercomputing. 75:1625-1640 |
| ISSN: | 1573-0484 0920-8542 |
| DOI: | 10.1007/s11227-018-2722-x |
| Popis: | Left ventricular non-compaction is characterized by the presence of multiple trabecules in the left ventricle myocardium, associated with multiple inter-trabecular recesses communicated with the ventricular cavity. The medical community needs an objective quantification of non-compacted cardiomyopathy, characterized by a trabeculated mass in the left ventricle myocardium. A software tool for the automatic quantification of the exact hyper-trabeculation degree in the left ventricle myocardium for a population of hypertrophic cardiomyopathy (QLVTHC) patients is developed and tested. End-diastolic cardiac magnetic resonance images of the patients are the input of the software, while the volumes of the compacted zones and the trabeculated zones are necessary to produce the percentage quantification of the trabecular zone with respect to the compacted zone. Significant improvements are obtained with respect to the manual process, by saving valuable diagnosis time. The development of a self-optimized software tool (SOST) based on the outputs of 50 patients with hypertrophic cardiomyopathy automatically produces the volumes of the compacted zones and the trabeculated zones, as a percentage quantification. Now, the SOST is tested with a different population of patients, with different characteristics. Besides, a parallelization for the detection of the external layer of the compacted zone allows the real-time analysis per slice in a patient, obtaining important speedups with regard to the QLVTHC proposed and the manual process used traditionally by cardiologists. |
| Databáze: | OpenAIRE |
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