Haematobiochemical Changes during Pain Management with Intraperitoneal Bupivacaine and Bupivacaine-dexmedetomidine in Dogs
| Autor: | Saurav Debnath, Hitesh Bayan ., Bedanga Konwar, Prava Mayengbam, Kalyan Sarma |
|---|---|
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Indian Journal of Animal Research. |
| ISSN: | 0976-0555 0367-6722 |
| DOI: | 10.18805/ijar.b-4848 |
| Popis: | Background: There is no gold standard to evaluate postoperative pain in animals. The study was conducted to evaluate haematobiochemical changes following intraperitoneal bupivacaine and bupivacaine-dexmedetomidine in dogs. Methods: Eighteen clinical cases of dogs requiring laparotomy were randomly divided into three groups viz. Group-B, BD and N comprising of six dogs in each. The animals were premedicated with glycopyrrolate, meloxicam and diazepam. Anaesthetic induction and maintenance was done by using propofol. Intraperitoneally bupivacaine, bupivacaine-dexmedetomidine and normal saline were infused in the three groups. The blood samples were collected prior to pre-medication at 0 min (base line), 30 min (after induction), 2 hrs and 24 hrs interval after intraperitoneal administration of drugs for estimation of haematobiochemical parameters. Result: The bupivacaine and dexmedetomidine combination reduces the serum glucose and cortisol level which might be indicative of lowered pain response. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|