Stereospecific Synthesis and Biological Evaluation of 9-α-D-Ribofuranosylguanine (α-Guanosine)

Autor:	M.-C. Bergogne, Jean-Louis Imbach, Gilles Gosselin
Rok vydání:	1990
Předmět:	chemistry.chemical_compound Stereospecificity chemistry Stereochemistry Yield (chemistry) Ribose Genetics Bioassay Guanosine Biochemistry Chemical synthesis Nucleoside Biological evaluation
Zdroj:	Nucleosides and Nucleotides. 9:81-87
ISSN:	0732-8311
DOI:	10.1080/07328319008045111
Popis:	Starting from D-ribose, the title compound 8 was prepared by a multistep approach in 6.6% overall yield. In none of the biological assays in which it was evaluated did α-guanosine demonstrate appreciable activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aeeb6019a6569c32fd15a2b5c310a796 https://doi.org/10.1080/07328319008045111 Zobrazit plný text záznamu