Clear-cell variant of mucoepidermoid carcinoma in the parotid gland:Case report and immunohistochemical study

Autor:	Tomoyuki Ohuchi, Tohru Kaku, Tatsuru Ikeda, Jiro Arai, Yoshihiro Abiko, Junichi Wakashima
Rok vydání:	1997
Předmět:	chemistry.chemical_classification Pathology medicine.medical_specialty Biology medicine.disease Parotid gland Pleomorphic adenoma medicine.anatomical_structure Salivary gland tumor chemistry Mucoepidermoid carcinoma Keratin medicine Immunohistochemistry Clear cell
Zdroj:	Oral Medicine & Pathology. 2:39-42
ISSN:	1882-1537 1342-0984
Popis:	We reported a case of a clear-cell variant, which is a histologically rare type of mucoepidermoid carcinoma, arising from the parotid gland of a 38-year-old Japanese female. Microscopically, most of the tumor nests were composed of clear cells surrounded by cuboidal epidermoid cells. A part of the tumor nest appeared to have tubular structures without clear cells. Although most of the clear cells had no reaction to PAS , alcian blue or mucicarmine, a few isolated clear cells showed positive reactions. Immunohistochemically, the tubular structures without clear cells showed positive reactions to keratin, S-100, CEA and EMA. The tumor nest of clear cells reacted to only keratin. From these results and a review of the existing literature, it is thought that the clear-cell variant of mucoepidermoid carcinoma may be closely related to pleomorphic adenoma.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ae78ba25e5c044dde1d58195b2f0b909 https://doi.org/10.3353/omp.2.39 Zobrazit plný text záznamu