| Popis: |
Objective: To determine the clinical and laboratory features, malignancy, outcome and their association in a Hispanic mestizo population with Inflammatory Idiopathic Myopathies (IIM). Material and methods: The medical records of Hispanic mestizo patients with dermatomyositis, polymyositis or overlap syndrome from a single center were reviewed. Several variables were studied with emphasis on malignancy. Results: We report the clinical and laboratorial features of 118 patients with IIM; the female to male ratio was 2.3:1. Elevated CK, proximal weakness, compatible biopsy and elevated LDH were the most frequent findings. Malignancy was found in 9,3%, gynecological tumors were the most common (55%). Mortality was 10.2%, mainly related to infections and respiratory failure. Conclusions: The overall rate of malignancy in this large series of patients with IIM was 9.3%. The majority of our patients reached a good outcome. No risk factors for malignancy were found. |
