Albumin-containing solutions equalize quantum yields of porphyrinic photosensitizers

Autor: Tatyana D. Muraviova, I. M. Belousova, T. K. Kris’ko, E. V. Kriukova
Rok vydání: 2018
Předmět:
Zdroj: 2018 International Conference Laser Optics (ICLO).
DOI: 10.1109/lo.2018.8435252
Popis: Fluorescent and singlet oxygen quantum yields of chlorin-based photosensitizer PhotoditazinTM were compared with those of porphyrin-based preparations in the environment of phosphate buffer and albumin. The albumin addition reduced both fluorescence and sensitizing properties of all the agents under study, equalizing quantum yield values of chlorin-based and porphyrin-based preparations. Complex formation between albumin and agent molecules was supposed to be the reason of the effect.
Databáze: OpenAIRE