Do ovarian reserve markers predict the subsequent pregnancy outcomes in women with recurrent pregnancy loss?
| Autor: | Nadiye Koroglu, Gonca Yetkin Yildirim, Esra Karakus, Hale Goksever Celik |
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| Rok vydání: | 2018 |
| Předmět: |
Antimullerian Hormone
Pregnancy 030219 obstetrics & reproductive medicine business.industry Biochemistry (medical) Clinical Biochemistry Physiology 030209 endocrinology & metabolism Antral follicle medicine.disease Biochemistry 03 medical and health sciences Follicle-stimulating hormone 0302 clinical medicine Medicine Subsequent pregnancy business Ovarian reserve Molecular Biology |
| Zdroj: | Turkish Journal of Biochemistry. 43:481-486 |
| ISSN: | 1303-829X 2017-0238 |
| Popis: | Objective(s): Chromosomal abnormalities are more commonly seen in embryos with decreased oocyte quality. Therefore aneuploidy due to diminished ovarian reserve may be one of the causative reasons of RPL. We investigated the relationship between ovarian reserve markers especially serum antimullerian hormone (AMH) level and antral follicle count (AFC) and recurrent pregnancy loss (RPL). Materials and methods: This prospective cross-sectional clinical trial including 88 women with RPL and 84 age-matched women without RPL. Results: There were statistically significant differences in body mass index, live birth number, menstrual cycle length, AFC and serum AMH level between groups. There was no statistically significant difference between groups regarding age, menstrual cycle regularity and serum follicle stimulating hormone (FSH) and estradiol (E2) levels. The percentage of women with levels of AMH Conclusion(s): Serum AMH levels and AFC can be assessed in patients with RPL as a part of the work up parameters. Lower Serum AMH levels and AFC especially may predict the quantity of oocytes that may be consequently be related with RPL. |
| Databáze: | OpenAIRE |
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