Synthesis of new dibenzofuran derivatives via Diels–Alder reaction of euparin with activated acetylenic esters
Autor: | Mohammad A. Khalilzadeh, Evan A. Sarina, Parvaneh Dastoorani, Malek Taher Maghsoodlou |
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Rok vydání: | 2016 |
Předmět: |
Ethanol
010405 organic chemistry Organic Chemistry Recrystallization (metallurgy) 010402 general chemistry 01 natural sciences Biochemistry Toluene 0104 chemical sciences Catalysis Dibenzofuran chemistry.chemical_compound Column chromatography chemistry Drug Discovery Organic chemistry Triphenylphosphine Diels–Alder reaction |
Zdroj: | Tetrahedron Letters. 57:314-316 |
ISSN: | 0040-4039 |
DOI: | 10.1016/j.tetlet.2015.12.021 |
Popis: | An efficient synthesis of novel dibenzofuran derivatives has been achieved via the Diels–Alder reaction of 1-(6-hydroxy-2-isopropenyl-1-benzofuran-yl)-1-ethanone, named euparin, with acetylenic diesters and propiolates in the presence of triphenylphosphine as a catalyst in toluene. All products were obtained by recrystallization from ethanol and did not require column chromatography. |
Databáze: | OpenAIRE |
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