11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range
Autor: | Arun Manickam, Arjang Hassibi, Nicholas Wood, Kae-Dyi You, Ritu Raj Singh, Yang Liu, Robert G. Kuimelis, Davood Shahrjerdi, Nader Gamini, Lei Pei |
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Rok vydání: | 2019 |
Předmět: |
Materials science
business.industry Dynamic range 020208 electrical & electronic engineering 02 engineering and technology Transducer CMOS Electrode 0202 electrical engineering electronic engineering information engineering Optoelectronics Instrumentation (computer programming) business Voltammetry Biosensor Electronic circuit |
Zdroj: | ISSCC |
DOI: | 10.1109/isscc.2019.8662507 |
Popis: | Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]–[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6]. |
Databáze: | OpenAIRE |
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