Thrombocytopenia in Systemic Lupus Erythematosus
| Autor: | Chang Hee Suh, Hyoun-Ah Kim, Moon Seung Soh, Yoo Jin Um, Jin Hee Jung, Young Hwan Ahn, Ju-Yang Jung |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
030203 arthritis & rheumatology
0301 basic medicine medicine.medical_specialty Lupus erythematosus business.industry Significant difference Retrospective cohort study General Medicine medicine.disease Response to treatment Gastroenterology Confidence interval Severe thrombocytopenia 03 medical and health sciences 030104 developmental biology 0302 clinical medicine hemic and lymphatic diseases Internal medicine Immunology Severity of illness medicine Platelet business |
| Zdroj: | Medicine. 95:e2818 |
| ISSN: | 0025-7974 |
| DOI: | 10.1097/md.0000000000002818 |
| Popis: | The aim of the study was to examine the clinical characteristics and prognosis according to severity of thrombocytopenia and response to treatment for thrombocytopenia in patients with systemic lupus erythematosus (SLE).We retrospectively evaluated 230 SLE patients with thrombocytopenia, and reviewed their clinical data and laboratory findings. Thrombocytopenia was defined as platelet counts under 100,000/mm, and patients were divided into 3 thrombocytopenia groups according to severity: mild (platelet counts >50,000/mm), moderate (>20,000/mm, ≤50,000/mm), and severe (≤20,000/mm). Clinical characteristics, treatments, and prognoses were compared among the groups. Furthermore, complete remission of thrombocytopenia was defined as platelet counts >100,000/mm after treatment.There was no significant difference in clinical or laboratory findings among the groups according to severity of thrombocytopenia. However, hemorrhagic complications were more frequent in severe thrombocytopenia (P |
| Databáze: | OpenAIRE |
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