Inhibition of metalloproteinase by futoenone derivatives

Autor:	James K. Chen, Li-An Yeh, Tsung-Ying Shen, Frans Baculi, Diane E. Gingrich
Rok vydání:	1995
Předmět:	chemistry.chemical_classification Metalloproteinase Chemistry Organic Chemistry Clinical Biochemistry Pharmaceutical Science Matrix metalloproteinase Inhibitory postsynaptic potential Biochemistry Enzyme Drug Discovery Molecular Medicine Molecular Biology
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 5:1637-1642
ISSN:	0960-894X
Popis:	Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases. The molecular modelings of these compounds indicate the preferred binding of the P2′ site of the enzymes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a9e856d57f63224f4434f8791bb8bd96 https://doi.org/10.1016/0960-894x(95)00282-x Zobrazit plný text záznamu Full Text from ScienceDirect