Polyaspartamide - a potential drug carrier

Autor:	Jaroslav Kálal, Vladimir Saudek, J. Vlasák, Jaroslav Drobník
Rok vydání:	2007
Předmět:	chemistry.chemical_classification Papain chemistry.chemical_compound Dextran chemistry General Engineering Parenteral route Organic chemistry Polymer Plasma expander Drug carrier
Zdroj:	Journal of Polymer Science: Polymer Symposia. 66:65-74
ISSN:	1936-0959 0360-8905
DOI:	10.1002/polc.5070660110
Popis:	and /3 copolymer [2]. Nevertheless, it was shown that the 2-hydroxyethyl derivative was well tolerated as a plasma expander [3], and in some parameters it was more advantageous than dextran. Possi- ble biodegradability was suggested in the same paper, but no data were given and the resistance to papain digestion was reported without details. However, biodegradability is an important prerequisite for the safe use of polymers as plasma expanders [4] and for any application by parenteral route
Databáze:	OpenAIRE
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