Levels of Activated FXII in Survivors of Myocardial Infarction – Association with Circulating Risk Factors and Extent of Coronary Artery Disease
Autor: | M. H. Stickland, Hans P. Kohler, Angela M. Carter, Peter J. Grant |
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Rok vydání: | 1998 |
Předmět: |
medicine.medical_specialty
Pathology Factor XIIa business.industry Cholesterol Insulin medicine.medical_treatment Hematology Fibrinogen medicine.disease Thrombosis Coronary artery disease chemistry.chemical_compound Insulin resistance chemistry Internal medicine medicine Cardiology Myocardial infarction business medicine.drug |
Zdroj: | Thrombosis and Haemostasis. 79:14-18 |
ISSN: | 2567-689X 0340-6245 |
DOI: | 10.1055/s-0037-1614210 |
Popis: | SummaryLittle data is available regarding the activated form of factor XIIa (FXIIa) in survivors of myocardial infarction. 292 Caucasian patients characterised for extent of coronary atheroma by angiography and for a past history of myocardial infarction and 77 healthy controls were included in the study. To investigate the relationship between coronary artery disease, activated factor XII and other circulating factors, we studied levels of FXIIa, cholesterol, triglycerides, fasting insulin, fibrinogen, FVII:C, t-PA antigen and PAI-1 antigen. Factor XIIa levels were higher in all patients [2.5 (2.3-2.6) ng/ml] and in patients with a history of MI [2.6 (2.4-2.9) ng/ml] than in controls [1.9 (1.7-2.1) ng/ml], p |
Databáze: | OpenAIRE |
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