Molecular-biological characteristics of rubella virus strains isolated in St. Petersburg

Autor: Gudkova Tm, Tsybalova Lm, Zh. V. Buzitskaya, A. K. Sirotkin, Oleg I. Kiselev, A. R. Prochukhanova, A. V. Karpov
Rok vydání: 2012
Předmět:
Zdroj: Molecular Biology. 46:605-608
ISSN: 1608-3245
0026-8933
Popis: In the surveillance of the incidence of rubella in the northwestern region of Russia, an analysis was conducted of swabs from the noses and pharynxes of 37 patients with rubella treated in Solovev District Military Clinical Hospital No. 442. To isolate the virus, the RK-13 cell line was used, in total 22 strains were allocated. The strains of the Rubella virus isolated in St. Petersburg during the 2007 outbreak belong to the 1E genotype. In the culture of RK-13 cells, changes of cellular morphogenesis and the formation of replicative complexes, as well as the shells of virions of rubella viruses, were detected.
Databáze: OpenAIRE