Basic Biological Sciences
| Autor: | Dorothea B. Fitzgerald, Robert J. Fitzgerald, Beatrice O. Adams, Kenneth W. Knox |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
0301 basic medicine
Molar Sucrose biology Strain (chemistry) 030206 dentistry biology.organism_classification Dental plaque medicine.disease Microbiology 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine chemistry Lactobacillus medicine General Dentistry Biological sciences |
| Zdroj: | Journal of Dental Research. 60:919-926 |
| ISSN: | 1544-0591 0022-0345 |
| DOI: | 10.1177/00220345810600051201 |
| Popis: | Thirty-two strains of Lactobacilli, comprising eight species and obtained from human dental plaque or other sources, were tested for cariogenic potential in gnotobiotic Sprague-Dawley rats receiving modified cariogenic Diet 2000. Seventeen of these strains were moderately to highly cariogenic, and only one, a strain of Lactobacillus lactis, was scored as non-cariogenic. The molar fissures were the predominant site of caries attack. Primary lesions of the smooth surfaces were infrequently seen, although these surfaces were often secondarily involved by the extension of fissure lesions. The preferential location of caries in the sheltered fissure sites was attributed to their inability to form adherent plaque deposits on the smooth surfaces of the teeth. Caries production by a strain of L. salivarius was equally severe on sucrose- or glucose-containing versions of Diet 2000, but glucose was less supportive of caries development than sucrose for a strain of L. fermentum. It is concluded that a wide variety of lactobacilli may be cariogenic under favorable environmental conditions. |
| Databáze: | OpenAIRE |
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