High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias
| Autor: | Petra B. Lücker, Steve Oh, Peter W. Zandstra, Emanuel J. P. Nazareth, Joel Ostblom, Shreya Shukla, Ting Yin, Manuel Alvarez |
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| Rok vydání: | 2013 |
| Předmět: |
Genetics
0303 health sciences Cellular differentiation Cell Biology Biology Biochemistry Embryonic stem cell Stem cell niche Cell biology 03 medical and health sciences 0302 clinical medicine Induced pluripotent stem cell Molecular Biology 030217 neurology & neurosurgery 030304 developmental biology Biotechnology |
| Zdroj: | Nature Methods. 10:1225-1231 |
| ISSN: | 1548-7105 1548-7091 |
| Popis: | This paper describes a platform for high-throughput image-based profiling of human pluripotent stem cells (hPSCs). It is used to quantify differentiation bias and endogenous signaling levels in hPSC lines. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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