Ergebnisse der Hormontherapie mit Aminoglutethimid (Rodazol®) beim Postmenopausalen metastasierten Mammakarzinom
| Autor: | Brockmann B, Uwe Schmidt, Geschke E |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Mammary gland Urology Obstetrics and Gynecology medicine.disease Metastatic breast cancer Metastasis Breast cancer Endocrinology medicine.anatomical_structure Internal medicine Maternity and Midwifery medicine Hormonal therapy Hormone therapy business Aminoglutethimide Tamoxifen medicine.drug |
| Zdroj: | Geburtshilfe und Frauenheilkunde. 51:276-279 |
| ISSN: | 1438-8804 0016-5751 |
| DOI: | 10.1055/s-2007-1023719 |
| Popis: | 44 postmenopausal women with progressive soft tissue, osseous and/or pleuropulmonal metastases of breast cancer were treated with aminoglutethimide (Rodazol) and hydrocortisone. 40 of the 41 patients, evaluated for treatment results, were pretreated hormonally and 17 were additionally pretreated chemotherapeutically. Objective remissions were achieved in 8 of the total of 41 patients (20%) and in 7 of the women (35%), who had previously responded to tamoxifen. Pain reduction was achieved in 4 of 17 cases (23%) with skeletal pain as the main symptom. The response rate was lower than expected. Primary hormonal therapy with Rodazol cannot be recommended in the osseous type of metastatic spread. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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