Molecular typing and antifungal drug susceptivity profile of Rhodotorula mucilaginosa from canine skin and ear canal

Autor:	Rui Kano, Honami Saika, Nobuo Murayama
Rok vydání:	2021
Předmět:	General Veterinary Broth microdilution Antifungal drug Drug susceptibility Biology Rhodotorula mucilaginosa Yeast Microbiology Molecular typing medicine.anatomical_structure medicine Ear canal Fluconazole medicine.drug
Zdroj:	Journal of Veterinary Medical Science. 83:1545-1548
ISSN:	1347-7439 0916-7250
Popis:	Rhodotorula mucilaginosa are saprophytic yeast, and opportunistic infections known as human rhodotorulosis are increasing in immunocompromised patients. In this study, we isolated R. mucilaginosa from pet dogs in Japan and determined the minimum inhibitory concentrations (MICs) of antifungal drugs on these isolates to investigate the drug susceptibility pattern. All 10 isolates according to the broth microdilution (BM) assay of the Clinical and Laboratory Standards Institute (CLSI) M27-A2 were resistance to azoles and genetically close to fluconazole (FLZ)-resistant human isolates of R. mucilaginosa. Due to resistance, it is expected that treatment will be difficult if they infect humans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a6824a33b56eedece114988a738a7220 https://doi.org/10.1292/jvms.21-0361 Zobrazit plný text záznamu