Intrathecal nociceptin displaces a PET ligand for its receptor in the brain at analgesic doses in rhesus monkeys (658.1)

Autor: Xia Shao, Gail Winger, James H. Woods, Peter Scott, Phillip S. Sherman, Phillip A. Saccone, Carole Quesada, Michael R. Kilbourn
Rok vydání: 2014
Předmět:
Zdroj: The FASEB Journal. 28
ISSN: 1530-6860
0892-6638
DOI: 10.1096/fasebj.28.1_supplement.658.1
Popis: The nociceptin receptor (NOP) has been investigated as a potential therapeutic target for pain control. Nociceptin, the endogenous ligand for NOP, produces analgesia in rodents and primates when gi...
Databáze: OpenAIRE