ChemInform Abstract: Anodic Amide Oxidations: Conformationally Restricted Peptide Building Blocks from the Direct Oxidation of Dipeptides

Autor:	Urszula Slomczynska, Garland R. Marshall, Kevin D. Moeller, Yvette M. Fobian, Fabrice Cornille, Denise D. Beusen
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Bicyclic molecule Stereochemistry Peptide General Medicine Electrochemistry Combinatorial chemistry Amino acid Anode chemistry.chemical_compound chemistry Yield (chemistry) Amide Lactam
Zdroj:	ChemInform. 26
ISSN:	0931-7597
Popis:	A pair of bicyclic lactam based conformationally restricted peptide mimetics have been synthesized in good yield by the direct anodic oxidation of dipeptides. This work highlights the simplicity of using electrochemistry to construct peptide mimetics and serves to further define the nature of the substituents that are compatible with an electrochemical procedure for annulating rings onto amino acid derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a4df869ee498689496e99df9c883083a https://doi.org/10.1002/chin.199508241 Zobrazit plný text záznamu Plný text