SKIN AND ORAL MOUTH ULCERS IN GRANULOMATOSIS WITH POLYANGIITIS (WEGENER’S GRANULOMATOSIS)
| Autor: | Gabrielle Calvi Veloso, Victor Angelo Martins Montalli, Paulo De Camargo Moraes, Lucas Novaes Teixeira, Daniela Prata Tacchelli, João Pedro Grandini Zeferino, Carolina Junqueira Da Costa Netto |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
business.industry Glomerulonephritis medicine.disease Dermatology Pathology and Forensic Medicine medicine.anatomical_structure Tongue Throat medicine Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Surgery Oral Surgery medicine.symptom business Granulomatosis with polyangiitis Mouth ulcers Vasculitis Nose Respiratory tract |
| Zdroj: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 130:e140 |
| ISSN: | 2212-4403 |
| Popis: | Granulomatosis with polyangiitis, formerly known as Wegener’s granulomatosis, is a potentially fatal systemic auto-immune disease, and it mainly affects small- and medium-sized blood vessels. It is characterized by necrotizing granulomatous lesions of the respiratory tract, vasculitis, and glomerulonephritis, and it could develop in various organs, especially the ear, nose and throat, lungs, and kidneys. In addition, 50% of cases show orbital involvement. This study presents a rare case of Wegener’s granulomatosis. A 62-year-old male had a complaint of thrush in both tongue margins and also had ocular lesions and involvement of the feet and hands. Due to the extensive ulcers we did an incisional biopsy, which revealed severe vasculitis and inflammatory infiltrate compatible with Wegener’s disease. Thereafter, we prescribed mouthwashing with benzydamine and a systemic corticosteroid. The treatment caused the lesions to disappear completely. |
| Databáze: | OpenAIRE |
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