ChemInform Abstract: BN 80927: A Novel Homocamptothecin with Inhibitory Activities on Both Topoisomerase I and Topoisomerase II

Autor:	Alain Rolland, Christophe Lanco, Olivier Lavergne, Marion Huchet, Hélène Coulomb, Dennis Bigg, Laurence Lesueur-Ginot, Danièle Demarquay, Jeremiah Harnett
Rok vydání:	2010
Předmět:	biology Topoisomerase General Medicine Inhibitory postsynaptic potential Molecular biology Human tumor chemistry.chemical_compound DU145 chemistry Cell culture biology.protein Homocamptothecin Cytotoxicity neoplasms DNA
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199949194
Popis:	BN 80927, a novel homocamptothecin derivative, inhibits both topoisomerase I and topoisomerase II mediated DNA relaxation and shows pronounced cytotoxicity against HT29, SKOV-3, DU145 and MCF7 human tumor cell lines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a3ac45dad2ceaf2e3351f53a6082eae9 https://doi.org/10.1002/chin.199949194 Zobrazit plný text záznamu Plný text