Radiothérapie de la chaîne mammaire interne dans les cancers du sein : état des lieux

Autor: Adrien Mélis, N.-H. Hau Desbat, Youlia M. Kirova, Lysian Cartier, Nicolas Magné, Pierre Auberdiac, G. de Laroche, A. Zioueche, Cyrus Chargari
Rok vydání: 2011
Předmět:
Zdroj: Cancer/Radiothérapie. 15:148-153
ISSN: 1278-3218
DOI: 10.1016/j.canrad.2010.07.634
Popis: Radiation therapy has a major role in the management of infiltrative breast cancers. However, there is no consensus for the prophylactic treatment of the internal mammary chain (IMC), with strategies that show strong differences according to centers and physicians. Indications for internal mammary chain radiotherapy are debated, since this treatment significantly increases the dose delivered to the heart and leads to potential technical difficulties. Important prospective data recently suggested that internal mammary chain radiotherapy would not be necessary, even in cases of internal or central tumor locations, or in patients with positive axillary lymph nodes. Although these data warrant confirmation by two other prospective trials, there is evidence that the indications for internal mammary chain radiotherapy should be careful and that high quality techniques should be used for decreasing the dose delivered to the heart. This review of literature presents the state of art on the radiotherapy of internal mammary chain, with special focus on the indications, techniques, and potential toxicity.
Databáze: OpenAIRE