| Autor: |
Geng Wang, Yuxuan Cheng, Ruikang K. Wang, Qinqin Zhang, Minh Nhan Le, Zhiying Xie |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Dynamics and Fluctuations in Biomedical Photonics XVII. |
| DOI: |
10.1117/12.2547619 |
| Popis: |
Pulsatile signals from the cutaneous blood flow could be informative for evaluating the health condition of an individual. One of the popular optical measuring devices, photoplethysmogram (PPG) is often used to detect the pulse signal from skin. However, the origin of the PPG signal still remains controversial. Benefiting from the non-invasive, label-free, 3D imaging tool, optical coherence tomography (OCT) is able to capture the intrinsic tissue signals at different penetration depth in high spatial and temporal resolution. Periodic pulse signal was observed by taking advantage of the optical microangiography (OMAG) algorithm which is sensitive to the motion of blood flow. The pulsatile pattern from the capillary and arteriole was successfully differentiated and their morphology showed distinct property at different local blood pressure. The pulse signal from the arteriole is more consistent and has similar waveform as the PPG signals. The result indicated that the PPG signal could be deceive by the mixing signal from the capillary bed and arterioles since it measures the total blood volume change in the plexuses. This study may shed some new light on understanding the mechanical property of how blood travel through different types of vasculature networks and elucidate its potential application in disease assessments. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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