Kynurenine and Tryptophan Levels in Patients With Schizophrenia and Elevated Antigliadin Immunoglobulin G Antibodies

Autor:	Bettina Konte, Janardan P. Pandey, Deanna L. Kelly, Kelly A. Stearns-Yoder, Ina Giegling, Dietmar Fuchs, Maureen Groer, Olaoluwa O. Okusaga, Teodor T. Postolache, William W. Eaton, Christopher A. Lowry, Lisa A. Brenner, Gloria Reeves, Dan Rujescu, Annette M. Hartmann, Marion Friedl, Thomas B. Cook, Andrew J. Hoisington
Rok vydání:	2016
Předmět:	chemical and pharmacologic phenomena behavioral disciplines and activities Immunoglobulin G Proinflammatory cytokine 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Immune system mental disorders medicine Applied Psychology biology business.industry biochemical phenomena metabolism and nutrition medicine.disease Pathophysiology 030227 psychiatry Psychiatry and Mental health chemistry Schizophrenia Immunology biology.protein bacteria Antibody Gliadin business 030217 neurology & neurosurgery Kynurenine
Zdroj:	Psychosomatic Medicine. 78:931-939
ISSN:	1534-7796 0033-3174
DOI:	10.1097/psy.0000000000000352
Popis:	ObjectiveSeveral studies have reported an association between nonceliac gluten sensitivity and schizophrenia. Immune and kynurenine (KYN) pathways have also been implicated in the pathophysiology of schizophrenia, and certain proinflammatory immune mediators may increase KYN and reduce trypt
Databáze:	OpenAIRE
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