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Introduction: Infantile hypertrophic pyloric stenosis (IHPS) is one of the most common surgical conditions of infancy. It`s prevalence ranges from 1.5 to 4 per 1000 live births. Different treatment modalities and procedures have been tried for the management of this common condition. Many innovations and approaches have been carried out for surgical management of IHPS. Open extramucosal pyloromyotomy, the original operation used to correct IHPS. Aim of the Study: The aim of this study was to evaluate and compare the outcome of Pyloromyotomy surgery among children with antibiotics or no antibiotics. Methods: This was a comparative study and was conducted in the Faculty of Pediatric Surgery of Bangladesh Shishu Hospital & Institute, Dhaka, Bangladesh during the period from January, 2020 to December, 2022. In our study we took 120 cases of Pyloromyotomy. All patients were randomized into two groups – Group A (Patients with antibiotics Ceftazidime) and Group B (Patients with no antibiotics). Periumbilical semicircular incision was made in all patients. Result: In total 120 patients from both the groups completed the study. In our study we found majority (67.5%) were less than 1 month & majority of our patients were male (75%) compared to female (25%). The Mean Age of group A & B was 33.5 ±11.2 & 32.1 ± 12.4 days respectively. Mean weight was 3.97 ± 0.8 & 4.02 ± 0.7 kg in group A & B respectively. Majority (13.33% & 10%) of patients had vomiting in group A & B respectively. Wound infection was 5% in group A & 6.67% in group B, stitch abscess was found 1.67% &1.67%, suture granuloma 5% & 1.67% in patients with antibiotics & no antibiotics respectively. Skin dehiscence was 6.67% in antibiotic group & 5% in no antibiotic group. Conclusion: In this study, we found major complications like wound infection, stitch abscess &skin dehiscence was present in our patients. However, there were no significant differences of these complications between antibiotic or no antibiotic ..... |