ASSESSMENT OF IL-33, TNF- α AND LEUKOTREINS B4 IN PATIENTS SERUM WITH ENTERIC FEVER

Autor: Khalil Ismail A. Mohammed, Saad Hasan Mohammed Ali, Suha A. Al-Fukhar, Wifaq M. Ali Al-Wattar, Jinan M. Mousa
Rok vydání: 2021
Předmět:
Zdroj: Journal of Experimental Biology and Agricultural Sciences. 9:851-854
ISSN: 2320-8694
DOI: 10.18006/2021.9(6).851.854
Popis: Salmonella typhoid and paratyphoid are transmitted mainly by the fecal-oral route. This study was designed to find the correlation between Salmonella and IgM, IgG, and the levels of interleukin-33, TNF-α, and LTB 4. The study was carried out from March 2020 to January 2021 for the detection of Salmonellosis in 100 suspected patients with age group ranging from 17 - 69 years, who attended Baghdad teaching hospitals that had been examined and defined as suspected cases by a specialized physician with the recording of clinical manifestation. The diagnosis was done by immunochromatography method, a blood sample was taken from the patient as well as other 30 healthy controls matching in age and gender. The study included measurement of the level of interleukin -33, Tumor necrosis Factor α, and Leukotreins B4 level in sera of patients and healthy control. The results indicated that anti –salmonella IgM positive in 54 cases, anti- salmonella IgG positive in 46 cases, and 18 positive cases with both IgM and IgG. The Level of interleukin 33, Tumor necrosis Factor – α increased significantly while the serum Leukotreins B4 level decreased significantly in patients sera as compared with healthy control.
Databáze: OpenAIRE