The effect of adding intrathecal magnesium sulphate to bupivacaine-fentanyl spinal anesthesia

Autor: Zaitang Wang, Jinguo Wang, Na Wang, Bo Shi
Rok vydání: 2020
Předmět:
Zdroj: Medicine. 99:e22524
ISSN: 1536-5964
0025-7974
DOI: 10.1097/md.0000000000022524
Popis: TRIAL DESIGN The current study is a meta-analysis designed to assess the effect of adding magnesium to a combination of intrathecal bupivacaine and fentanyl. METHODS The protocol was registered in PROSPERO with the number CRD42020177618. PubMed, Cochrane library, Web of Science, and Google Scholar were searched for randomized controlled trials investigating the effect of adding magnesium to a combination of intrathecal bupivacaine and fentanyl. The continuous data were presented as Ratio of means (RoM). Risk ratio (RR) along with 95% confidence interval (CI) was utilized to assess the dichotomous data. RESULTS Ten trials were involved in the present study with 720 adult patients. Compared with control, intrathecal magnesium prolonged time to the first analgesic requirement by an estimate of 1.23 (RoM: 1.23; 95%CI: 1.13-1.33; P
Databáze: OpenAIRE