Effectiveness of the First Trimester Samrakshan Protocol for the Identification of Pregnant Women at High Risk for Preterm Pre-eclampsia

Autor: Rijo Mathew Choorakuttil, Bavaharan Rajalingam, Shilpa R. Satarkar, Lalit K. Sharma, Anjali Gupta, Akanksha Baghel, Neelam Jain, Sandhya Dhankar, Kavita Aneja, Gulab Chhajer, Somya Dwivedi, Tejashree Y. Patekar, Eesha Rajput, Praveen K. Nirmalan
Rok vydání: 2022
Předmět:
Zdroj: Indian Journal of Radiology and Imaging. 33:098-100
ISSN: 1998-3808
0971-3026
Popis: Aim To determine the effectiveness of the first trimester Samrakshan protocol for the identification of pregnant women at high risk for preterm pre-eclampsia (PE). Methods Samrakshan uses a protocol that integrates routine first-trimester ultrasound assessment at 11 to 14 gestation weeks with the measurement of mean arterial blood pressure and mean uterine artery pulsatility index assessment to determine a customized risk for preterm PE and fetal growth restriction. Based on the risk assessment, pregnant women are classified as high or low risk. Results The protocol had a high specificity (90.4%, 95% CI: 89.4%, 91.2%) and negative predictive value (98.1%, 95% CI: 97.6%, 99%) for preterm PE. The odds ratio and positive likelihood ratio for preterm PE were 16.7 (95% CI: 12.3, 22.6) and 6.64 (95% CI: 5.77, 7.63), respectively. Conclusions The positive likelihood ratio and odds ratios indicate that pregnant women identified as high risk for preterm PE using the first-trimester protocol of Samrakshan are significantly more likely to develop preterm PE than low-risk women.
Databáze: OpenAIRE