Synthesis and Chemico-Pharmaceutical Characteristics of a Somatostatin Analog with Antitumor Activity

Autor:	S. V. Ustinkina, Z. S. Shprakh, A. P. Bud'ko, L. P. Sushinina, I. V. Yartseva, A. P. Smirnova, L. I. Smirnova, N. I. Zimakova, E. V. Ignat’eva
Rok vydání:	2014
Předmět:	Pharmacology Antitumor activity endocrine system Somatostatin Chemistry Drug Discovery Pharmacology toxicology Somatostatin analog Combinatorial chemistry health care economics and organizations hormones hormone substitutes and hormone antagonists Control methods
Zdroj:	Pharmaceutical Chemistry Journal. 48:159-162
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-014-1069-8
Popis:	An analog of somatostatin with hormonal and antitumor activity was synthesized. An optimum synthesis method was developed, yielding standard pharmaceutical somatostatin analog substance for preclinical and clinical studies. A quality control method was developed for inclusion in the draft manufacturer’s pharmacopeia monograph for pharmacological somatostatin analog substance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9ef72cab79543628939492f47e09dd7e https://doi.org/10.1007/s11094-014-1069-8 Zobrazit plný text záznamu Plný text ve formátu PDF